Dettmers' Rising Sun is pleased to now provide clients with a new product in wound healing.  Our veterinarian has been working for a number of years on producing this exciting product that has changed the way we treat wounds here at the farm.  Please take a look at some of the information that we have provided here.  We now keep Eclipse Wound Care products on hand at all times and it has proven itself over time to be effective at preventing scars and speeding healing.  The following article was found on the BeluMedX website.  If you are interested in purchasing these products, please contact us, and we will make sure to get it packaged and shipped to you as quickly as possible. 

ECLIPSE

The research team at BeluMedX uses Biotechnology combined with research in growth factors and tissue engineering to evaluate new wound healants for nonhealing equine wounds. One of our major focus areas is the use of natural compounds derived from horse blood combined with antioxidants and vitamins and minerals to induce regenerative wound healing. Our healing products contain all-natural compounds including Vitamin C, aloe vera and growth factors in physiologic balance from the horses' own blood. These wound healing products have the capacity to improve the quality of life of your horse if it becomes wounded, and may extend the life of the animal. Our products have produced unprecedented success in generating quality healing in a short time in the hard-to-heal, poorly vascularized lower equine limb. Conventional treatments for many skin problems, especially topical steroids, are suppressive in nature and potentially toxic. Although helpful to clean infected wounds, hydrogen peroxide and alcohol are harsh chemicals that can damage healing tissue if used in excess, for example for the treatment of chronic wounds. Use of our natural wound healing products eliminates the need for these chemicals because they contain nature's most powerful natural wound healing factors including growth factor proteins, vitamins, minerals and antioxidants possessing anti-bacterial, anti-fungal and tissue regenerating activity. Our new wound healants do NOT contain immunosuppressive or harsh substances. We use all-natural compounds.

Antioxidants in our Platelet-Rich Plasma

Vitamin C
Our line of platelet-rich plasma wound care products contain natural compounds proven to promote rapid wound healing. One antioxidant in our product is vitamin C or ascorbic acid. What do antioxidants do that makes them so effective? When an organism uses oxygen at the cellular level, unstable molecules termed "free radicals" are generated. Free radicals include "reactive oxygen species" such as superoxides and hydrogen peroxide and "reactive nitrogen species" such as nitric oxide and peroxynitrites. Free radicals are unstable oxygen molecules that cause damage to cellular components such as DNA, proteins or lipids and can induce cell death. The body generates free radicals all the time, and they are generally neutralized by biochemical reactions. Antioxidants trap and neutralize excess free radicals. The levels of free radicals are very high in a wound due to damage to cells in wounded tissue. Immune cells migrating into the wound bed induce inflammation and release free radicals that damage nearby cells. In an injury, antioxidants in the body may not be able to neutralize all of the damage because the amount of free radicals is very high due to the tissue injury. The use of topical antioxidants can thus be very helpful to minimize damage and promote rapid healing.
Vitamin C helps prevent depletion of antioxidants stored in the skin. By this mechanism, vitamin C prevents damage by free radicals. As an antioxidant, Vitamin C also induces accelerated healing of the skin and stimulates collagen production. Vitamin C is a free radical scavenger that promotes healing (Lewis and Elvin-Lewis, 1997) by accelerating differentiation or maturation of skin cells (Lopez-Lluch, et al., 2001; Savini, et al., 2002). Vitamin C is a known stimulator of collagen production (Nowak, et al., 2000). For example, topical vitamin C reverses damage to skin induced by aging (Traikovich, 1999). Aging can damage the collagen fibers below the skin's surface and cause the skin to fall into the grooves creating wrinkles. Topical vitamin C restores collagen fibers to a firm youthful state.
Our platelet-rich plasma gel product stimulates the formation of good collagen. Tissues not treated with our product have poorly organized collagen (Carter, et al., 2003). Our platelet-rich plasma gel creates healed tissues with a better type of collagen. The resultant tissue contains dense, tightly packed, organized collagen fibers (Carter, et al., 2003) similar to collagen in uninjured tissue. Platelet-rich plasma gel creates regenerated tissue that matures or differentiates faster than untreated (control) tissues, thus the tissue heals more quickly than untreated tissues (Carter, et al., 2003).
Aloe vera
Our Eclipse® Brand Wound Healing Aid is a wound healant that contains aloe vera and is made from platelet-rich plasma. Aloe vera is a well-known natural healant used for centuries to promote healing of the skin (Lewis and Elvin-Lewis, 1997). For generations, Native Americans have taken advantage of the healing capacity of the raw juice of the leaf of the aloe plant by creating a salve for the treatment of thermal burns, chemical burns, sunburns, insect bites and wounds (Mary Summer Rain, 1990). One report dates from 1935 when aloe vera was used to treat a burn: within 5 weeks healing was complete with full skin regeneration and no scarring (Collins and Collins, 1935). Aloe vera is also anti-bacterial (Lorenzetti et al., 1964) and anti-fungal. In addition, aloe vera is an antioxidant that serves as a popular aid for the treatment of burning, itching, minor cuts and thermal burns. Scarring is prevented in the healed wound with the use of aloe vera (Lewis and Elvin-Lewis, 1997). Aloe vera is an anti-inflammatory and promoted wound healing when applied to a second degree burn (Somboonwong, et al., 2000). When tested in granulation tissue (or the "scab") in the rat, aloe vera increased collagen synthesis, collagen content and the degree of collagen crosslinking (Chithra, et al., 1998a; Chithra, et al., 1998b). Fresh leaf pulp extract of aloe vera protected against oxidant-induced cellular damage (Singh, et al., 2000), demonstrating the antioxidant properties of aloe vera's healing benefits. The anti-bacterial, anti-fungal, antioxidant, and anti-inflammatory properties of aloe vera combined with it's ability to increase collagen content without the creation of a scar makes it an ideal natural healant.
Our approach to wound treatment is unique because we use all natural healants containing growth factors from horse blood combined with antioxidants and vitamins and minerals that have been used for centuries as wound healing aids. This novel, natural combination of healing compounds in physiologic balance produces faster healing and regenerated tissue with high quality collagen (Carter, et al., 2003). In summary, when applied to hard-to-heal or routine wounds, our product creates tissue similar to uninjured tissue (Carter, et al., 2003).